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How is the effectiveness of immune surveillance impacted by the spatial distribution of spreading infections?
What effect does the spatial distribution of infected cells have on the efficiency of their removal by immune cells, such as cytotoxic T lymphocytes (CTL)? If infected cells spread in clusters, CTL may initially be slow to locate them but subsequently kill more rapidly than in diffuse infections. We...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528487/ https://www.ncbi.nlm.nih.gov/pubmed/26150655 http://dx.doi.org/10.1098/rstb.2014.0289 |