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Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes

BACKGROUND: Many researchers have suggested that the glutamatergic system may be involved in the effects of antidepressant therapies. We investigated the effects of doxepin, imipramine, and fluoxetine on the excitatory amino acid transporter type 3 (EAAT3). METHODS: EAAT3 was expressed in Xenopus oo...

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Detalles Bibliográficos
Autores principales: Park, Hye Jin, Baik, Hee Jung, Kim, Dong Yeon, Lee, Guie Yong, Woo, Jae Hee, Zuo, Zhiyi, Chung, Rack Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528682/
https://www.ncbi.nlm.nih.gov/pubmed/26253075
http://dx.doi.org/10.1186/s12871-015-0098-5