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Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes
BACKGROUND: Many researchers have suggested that the glutamatergic system may be involved in the effects of antidepressant therapies. We investigated the effects of doxepin, imipramine, and fluoxetine on the excitatory amino acid transporter type 3 (EAAT3). METHODS: EAAT3 was expressed in Xenopus oo...
Autores principales: | Park, Hye Jin, Baik, Hee Jung, Kim, Dong Yeon, Lee, Guie Yong, Woo, Jae Hee, Zuo, Zhiyi, Chung, Rack Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528682/ https://www.ncbi.nlm.nih.gov/pubmed/26253075 http://dx.doi.org/10.1186/s12871-015-0098-5 |
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