Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination

[Image: see text] The CuH-catalyzed hydroamination of alkenes and alkynes using a silane and an amine transfer reagent represents a simple strategy to access chiral amine products. We have recently reported methods to prepare chiral amines with high efficiency and stereoselectivity using this approa...

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Detalles Bibliográficos
Autores principales: Niu, Dawen, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528777/
https://www.ncbi.nlm.nih.gov/pubmed/26144542
http://dx.doi.org/10.1021/jacs.5b05446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528777/
https://www.ncbi.nlm.nih.gov/pubmed/26144542
http://dx.doi.org/10.1021/jacs.5b05446

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