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Molecular cytogenetic studies characterizing a novel complex karyotype with an uncommon 5q22 deletion in childhood acute myeloid leukemia

Deletions in the long arm of chromosome 5 or loss of the whole chromosome are rare in childhood Acute Myeloid Leukemia (AML) patients. It is also unknown if the wide variety of breakpoints have diverging implications in the patient’s outcome. Despite -5/5q- abnormalities have usually been described...

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Detalles Bibliográficos
Autores principales: de Figueiredo, Amanda Faria, Capela de Matos, Roberto Rodrigues, Othman, Moneeb A. K., Liehr, Thomas, da Costa, Elaine Sobral, Land, Marcelo Geradin Poirot, Ribeiro, Raul C., Abdelhay, Eliana, Silva, Maria Luiza Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528810/
https://www.ncbi.nlm.nih.gov/pubmed/26257826
http://dx.doi.org/10.1186/s13039-015-0167-y