Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

Multiple sclerosis (MS) involves an aberrant autoimmune response and progressive failure of remyelination in the central nervous system (CNS). Prevention of neural degeneration and subsequent disability requires remyelination through the generation of new oligodendrocytes, but current treatments exc...

Descripción completa

Detalles Bibliográficos
Autores principales: Najm, Fadi J., Madhavan, Mayur, Zaremba, Anita, Shick, Elizabeth, Karl, Robert T., Factor, Daniel C., Miller, Tyler E., Nevin, Zachary S., Kantor, Christopher, Sargent, Alex, Quick, Kevin L., Schlatzer, Daniela M., Tang, Hong, Papoian, Ruben, Brimacombe, Kyle R., Shen, Min, Boxer, Matthew B., Jadhav, Ajit, Robinson, Andrew P., Podojil, Joseph R., Miller, Stephen D., Miller, Robert H., Tesar, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528969/
https://www.ncbi.nlm.nih.gov/pubmed/25896324
http://dx.doi.org/10.1038/nature14335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528969/
https://www.ncbi.nlm.nih.gov/pubmed/25896324
http://dx.doi.org/10.1038/nature14335

Ejemplares similares