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Beyond the Mean: Quantile Regression to Explore the Association of Air Pollution with Gene-Specific Methylation in the Normative Aging Study

BACKGROUND: Air pollution has been related to mean changes in outcomes, including DNA methylation. However, mean regression analyses may not capture associations that occur primarily in the tails of the outcome distribution. OBJECTIVES: In this study, we examined whether the association between part...

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Detalles Bibliográficos
Autores principales: Bind, Marie-Abele C., Coull, Brent A., Peters, Annette, Baccarelli, Andrea A., Tarantini, Letizia, Cantone, Laura, Vokonas, Pantel S., Koutrakis, Petros, Schwartz, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529003/
https://www.ncbi.nlm.nih.gov/pubmed/25769179
http://dx.doi.org/10.1289/ehp.1307824