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Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice

BACKGROUND: Ozone is a highly toxic air pollutant and global health concern. Mechanisms of genetic susceptibility to ozone-induced lung inflammation are not completely understood. We hypothesized that Notch3 and Notch4 are important determinants of susceptibility to ozone-induced lung inflammation....

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Detalles Bibliográficos
Autores principales: Verhein, Kirsten C., McCaw, Zachary, Gladwell, Wesley, Trivedi, Shweta, Bushel, Pierre R., Kleeberger, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529014/
https://www.ncbi.nlm.nih.gov/pubmed/25658374
http://dx.doi.org/10.1289/ehp.1408852