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Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification

Chromatin remodelling proteins are essential for different aspects of metazoan biology, yet functional details of why these proteins are important are lacking. Although it is possible to describe the biochemistry of how they remodel chromatin, their chromatin-binding profiles in cell lines, and gene...

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Detalles Bibliográficos
Autores principales: O'Shaughnessy-Kirwan, Aoife, Signolet, Jason, Costello, Ita, Gharbi, Sarah, Hendrich, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529036/
https://www.ncbi.nlm.nih.gov/pubmed/26116663
http://dx.doi.org/10.1242/dev.125450