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Promotion of Erythropoietic Differentiation in Hematopoietic Stem Cells by SOCS3 Knock-Down

Suppressor of cytokine signaling 3 (SOCS3) plays an important role in mice fetal liver erythropoiesis, but the roles of SOCS3 in human hematopoietic stem cells (HSCs) have not been well investigated. In the present study, lentiviral small interference RNA expression vectors (shRNA) of SOCS3 were con...

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Detalles Bibliográficos
Autores principales: Liu, Yu-xiao, Dong, Xing, Gong, Feng, Su, Ning, Li, Su-bo, Zhang, Hai-tao, Liu, Jia-ling, Xue, Jing-hui, Ji, Shou-ping, Zhang, Zhi–wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529111/
https://www.ncbi.nlm.nih.gov/pubmed/26252772
http://dx.doi.org/10.1371/journal.pone.0135259