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Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection

Neutrophil extracellular traps (NETs) are released, as neutrophils die in vitro, in a process requiring hours, leaving a temporal gap for invasive microbes to exploit. Functional neutrophils undergoing NETosis have not been documented. During Gram-positive skin infections, we directly visualized liv...

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Detalles Bibliográficos
Autores principales: Yipp, Bryan G., Petri, Björn, Salina, Davide, Jenne, Craig N., Scott, Brittney N. V., Zbytnuik, Lori D., Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H. Christopher, Malawista, Stephen E., de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529131/
https://www.ncbi.nlm.nih.gov/pubmed/22922410
http://dx.doi.org/10.1038/nm.2847