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Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection
Neutrophil extracellular traps (NETs) are released, as neutrophils die in vitro, in a process requiring hours, leaving a temporal gap for invasive microbes to exploit. Functional neutrophils undergoing NETosis have not been documented. During Gram-positive skin infections, we directly visualized liv...
Autores principales: | Yipp, Bryan G., Petri, Björn, Salina, Davide, Jenne, Craig N., Scott, Brittney N. V., Zbytnuik, Lori D., Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H. Christopher, Malawista, Stephen E., de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529131/ https://www.ncbi.nlm.nih.gov/pubmed/22922410 http://dx.doi.org/10.1038/nm.2847 |
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