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Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung

Some Pseudomonas aeruginosa strains including Australian Epidemic Strain-1 (AES-1 or AUS-01) cause persistent chronic infection in cystic fibrosis (CF) patients, with greater morbidity and mortality. Factors conferring persistence are largely unknown. Previously we analysed the transcriptomes of AES...

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Detalles Bibliográficos
Autores principales: Harmer, Christopher J., Wynn, Matthew, Pinto, Rachel, Cordwell, Stuart, Rose, Barbara R., Harbour, Colin, Triccas, James A., Manos, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529145/
https://www.ncbi.nlm.nih.gov/pubmed/26252386
http://dx.doi.org/10.1371/journal.pone.0134229