Cargando…

Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung

Some Pseudomonas aeruginosa strains including Australian Epidemic Strain-1 (AES-1 or AUS-01) cause persistent chronic infection in cystic fibrosis (CF) patients, with greater morbidity and mortality. Factors conferring persistence are largely unknown. Previously we analysed the transcriptomes of AES...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harmer, Christopher J., Wynn, Matthew, Pinto, Rachel, Cordwell, Stuart, Rose, Barbara R., Harbour, Colin, Triccas, James A., Manos, Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529145/ https://www.ncbi.nlm.nih.gov/pubmed/26252386 http://dx.doi.org/10.1371/journal.pone.0134229

Ejemplares similares

Correction: Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung
Publicado: (2015)

Catechol 1,2-Dioxygenase is an Analogue of Homogentisate 1,2-Dioxygenase in Pseudomonas chlororaphis Strain UFB2
por: Setlhare, Boitumelo, et al.
Publicado: (2018)

Proteomic profiling of Pseudomonas aeruginosa AES-1R, PAO1 and PA14 reveals potential virulence determinants associated with a transmissible cystic fibrosis-associated strain
por: Hare, Nathan J, et al.
Publicado: (2012)

Molecular docking analysis of nitisinone with homogentisate 1,2 dioxygenase
por: Zolfaghari, Narges
Publicado: (2017)

Homogentisate 1,2 Dioxygenase is Expressed in Human Osteoarticular Cells: Implications in Alkaptonuria
por: Laschi, Marcella, et al.
Publicado: (2012)

Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2‐dioxygenase deficiency in the liver is responsible for homogentisic acid‐derived ochronotic pigmentation
por: Wilson, Peter J. M., et al.
Publicado: (2020)

Homogentisate 1,2-dioxygenase (HGD) gene variants in young Egyptian patients with alkaptonuria
por: Abdelkhalek, Zeinab S., et al.
Publicado: (2023)

Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
por: Hughes, Juliette H, et al.
Publicado: (2019)

Loss of Homogentisate 1,2-Dioxygenase Activity in Bacillus anthracis Results in Accumulation of Protective Pigment
por: Han, Hesong, et al.
Publicado: (2015)

Single Amino Acid Substitution in Homogentisate Dioxygenase Affects Melanin Production in Bacillus thuringiensis
por: Yang, Wenjun, et al.
Publicado: (2018)

First Report of a Deletion Encompassing an Entire Exon in the Homogentisate 1,2-Dioxygenase Gene Causing Alkaptonuria
por: Habbal, Mohammad Zouheir, et al.
Publicado: (2014)

Pseudomonas aeruginosa AES-1 Exhibits Increased Virulence Gene Expression during Chronic Infection of Cystic Fibrosis Lung
por: Naughton, Sharna, et al.
Publicado: (2011)

A robust bacterial high-throughput screening system to evaluate single nucleotide polymorphisms of human homogentisate 1,2-dioxygenase in the context of alkaptonuria
por: Lequeue, Sien, et al.
Publicado: (2022)

Binding interaction of a ring-hydroxylating dioxygenase with fluoranthene in Pseudomonas aeruginosa DN1
por: Xue, Shu-Wen, et al.
Publicado: (2021)

Does Pseudomonas aeruginosa Colonization Affect Exercise Capacity in CF?
por: Kampouras, Asterios, et al.
Publicado: (2019)

A diagnostic PCR assay for the detection of an Australian epidemic strain of Pseudomonas aeruginosa
por: Williams, Heidi L, et al.
Publicado: (2010)

Conversion of Squid Pen to Homogentisic Acid via Paenibacillus sp. TKU036 and the Antioxidant and Anti-Inflammatory Activities of Homogentisic Acid
por: Wang, San-Lang, et al.
Publicado: (2016)

Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection
por: Clancy, J P, et al.
Publicado: (2013)

Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice
por: Sandri, Angela, et al.
Publicado: (2018)

Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway
por: Hoffman, Lucas R., et al.
Publicado: (2010)

The Microbiology of Non-aeruginosa Pseudomonas Isolated From Adults With Cystic Fibrosis: Criteria to Help Determine the Clinical Significance of Non-aeruginosa Pseudomonas in CF Lung Pathology
por: Moore, John E., et al.
Publicado: (2022)

Emergence and Spread of Epidemic Multidrug-Resistant Pseudomonas aeruginosa
por: Miyoshi-Akiyama, Tohru, et al.
Publicado: (2017)

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa
por: Burr, Lucy D., et al.
Publicado: (2018)

HGDiscovery: An online tool providing functional and phenotypic information on novel variants of homogentisate 1,2- dioxigenase
por: Karmakar, Malancha, et al.
Publicado: (2022)

Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1
por: Balderas-Hernández, Víctor E, et al.
Publicado: (2014)

The B Lymphocyte Differentiation Factor (BAFF) Is Expressed in the Airways of Children with CF and in Lungs of Mice Infected with Pseudomonas aeruginosa
por: Neill, Daniel R., et al.
Publicado: (2014)

Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French CF registry
por: Vongthilath, Réchana, et al.
Publicado: (2019)

Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages
por: Weidenfeld, Ina, et al.
Publicado: (2019)

Transcriptional and protein structural characterization of homogentisate phytyltransferase genes in barley, wheat, and oat
por: Zeng, Zhanghui, et al.
Publicado: (2023)

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy
por: Jabir, Majid Sakhi, et al.
Publicado: (2015)

3,4-Dihydroxyphenylacetate 2,3-dioxygenase from Pseudomonas aeruginosa: An Fe(II)-containing enzyme with fast turnover
por: Pornsuwan, Soraya, et al.
Publicado: (2017)

INCREASING BURDEN OF ANTIMICROBIAL RESISTANCE IN PSEUDOMONAS AERUGINOSA FROM ADULT PATIENTS WITH CYSTIC FIBROSIS (CF) IN NORTHERN IRELAND: THEN AND NOW
por: Gramegna, Andrea, et al.
Publicado: (2018)

Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial
por: Hewer, Simon C Langton, et al.
Publicado: (2020)

Developing an international Pseudomonas aeruginosa reference panel
por: De Soyza, Anthony, et al.
Publicado: (2013)

Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain
por: Moore, Matthew P., et al.
Publicado: (2021)

Homogentisic Acid and Gentisic Acid Biosynthesized Pyomelanin Mimics: Structural Characterization and Antioxidant Activity
por: Al Khatib, Maher, et al.
Publicado: (2021)

Evaluation of tests to predict metallo-β-lactamase in cystic fibrosis (CF) and non-(CF) Pseudomonas
por: Perez, Leandro Reus Rodrigues, et al.
Publicado: (2014)

Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR
por: Young, Robert L., et al.
Publicado: (2011)

Aspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF Airway
por: Reece, Emma, et al.
Publicado: (2018)

Phenotypic and Genotypic Comparison of Epidemic and Non-Epidemic Strains of Pseudomonas aeruginosa from Individuals with Cystic Fibrosis
por: Duong, Jessica, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_stmoe0miqo6rk9eqcl1nt0e3g0