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AdHu5Ag85A Respiratory Mucosal Boost Immunization Enhances Protection against Pulmonary Tuberculosis in BCG-Primed Non-Human Primates

Persisting high global tuberculosis (TB) morbidity and mortality and poor efficacy of BCG vaccine emphasizes an urgent need for developing effective novel boost vaccination strategies following parenteral BCG priming in humans. Most of the current lead TB vaccine candidates in the global pipeline we...

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Detalles Bibliográficos
Autores principales: Jeyanathan, Mangalakumari, Shao, Zhongqi, Yu, Xuefeng, Harkness, Robin, Jiang, Rong, Li, Junqiang, Xing, Zhou, Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529167/
https://www.ncbi.nlm.nih.gov/pubmed/26252520
http://dx.doi.org/10.1371/journal.pone.0135009