Reduced Na(v)1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics

Na(v)1.6 is a major voltage-gated sodium channel in the central and peripheral nervous systems. Within neurons, the channel protein is concentrated at the axon initial segment and nodes of Ranvier, where it functions in initiation and propagation of action potentials. We examined the role of Na(v)1....

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Detalles Bibliográficos
Autores principales: Pal, Dinesh, Jones, Julie M., Wisidagamage, Stella, Meisler, Miriam H., Mashour, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529172/
https://www.ncbi.nlm.nih.gov/pubmed/26252017
http://dx.doi.org/10.1371/journal.pone.0134960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529172/
https://www.ncbi.nlm.nih.gov/pubmed/26252017
http://dx.doi.org/10.1371/journal.pone.0134960

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