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Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis

MicroRNA-155 has been shown to play a role in immune activation and inflammation, and is suppressed by IL-10, an important anti-inflammatory cytokine. The established involvement of IL-10 in the murine model of Borrelia burgdorferi-induced Lyme arthritis and carditis allowed us to assess the interpl...

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Detalles Bibliográficos
Autores principales: Lochhead, Robert B., Zachary, James F., Dalla Rosa, Luciana, Ma, Ying, Weis, John H., O’Connell, Ryan M., Weis, Janis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529177/
https://www.ncbi.nlm.nih.gov/pubmed/26252010
http://dx.doi.org/10.1371/journal.pone.0135142