TGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling Mechanisms

Fibroblasts are major cellular components of the breast cancer stroma, and influence the growth, survival and invasion of epithelial cells. Compared to normal tissue fibroblasts, carcinoma associated fibroblasts (CAFs) show increased expression of numerous soluble factors including growth factors an...

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Detalles Bibliográficos
Autores principales: Fang, Wei Bin, Mafuvadze, Benford, Yao, Min, Zou, An, Portsche, Mike, Cheng, Nikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529193/
https://www.ncbi.nlm.nih.gov/pubmed/26252654
http://dx.doi.org/10.1371/journal.pone.0135063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529193/
https://www.ncbi.nlm.nih.gov/pubmed/26252654
http://dx.doi.org/10.1371/journal.pone.0135063

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