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Polymyxin E Induces Rapid Paenibacillus polymyxa Death by Damaging Cell Membrane while Ca(2+) Can Protect Cells from Damage

Polymyxin E, produced by Paenibacillus polymyxa, is an important antibiotic normally against Gram-negative pathogens. In this study, we found that polymyxin E can kill its producer P. polymyxa, a Gram-positive bacterium, by disrupting its cell membrane. Membrane damage was clearly revealed by detect...

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Detalles Bibliográficos
Autores principales: Yu, Zhiliang, Cai, Yuanning, Qin, Wangrong, Lin, Jianxun, Qiu, Juanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529208/
https://www.ncbi.nlm.nih.gov/pubmed/26252512
http://dx.doi.org/10.1371/journal.pone.0135198