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Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis

Cryptococcus neoformans is the most common cause of fungal meningoencephalitis in AIDS patients. Depletion of CD4 cells, such as occurs during advanced AIDS, is known to be a critical risk factor for developing cryptococcosis. However, the role of HIV-induced innate inflammation in susceptibility to...

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Detalles Bibliográficos
Autores principales: Sionov, Edward, Mayer-Barber, Katrin D., Chang, Yun C., Kauffman, Keith D., Eckhaus, Michael A., Salazar, Andres M., Barber, Daniel L., Kwon-Chung, Kyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529209/
https://www.ncbi.nlm.nih.gov/pubmed/26252005
http://dx.doi.org/10.1371/journal.ppat.1005040