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Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation

BACKGROUND AND AIMS: Plasmacytoid dendritic cells (pDCs) are a small subset of dendritic cells and the main producers of type I interferons. Besides their contribution to tolerance, they are known to be involved in autoimmune diseases and have recently been implicated in atherosclerosis. However, th...

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Detalles Bibliográficos
Autores principales: Mandl, Manuela, Drechsler, Maik, Jansen, Yvonne, Neideck, Carlos, Noels, Heidi, Faussner, Alexander, Soehnlein, Oliver, Weber, Christian, Döring, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529211/
https://www.ncbi.nlm.nih.gov/pubmed/26252890
http://dx.doi.org/10.1371/journal.pone.0134176