Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis Mediated by YhdE Dimerization

YhdE is a Maf-like (multicopy associated filamentation) protein that primarily acts as dTTPase to hydrolyze dTTP into dTMP and two phosphate molecules in cell metabolism pathway. Two crystal structures of YhdE have been previously determined, representing the open and closed active site conformation...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Jiang, Jiahong, Li, Xichen, Tan, Hongwei, Zheng, Jimin, Chen, Guangju, Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529217/
https://www.ncbi.nlm.nih.gov/pubmed/26252214
http://dx.doi.org/10.1371/journal.pone.0134879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529217/
https://www.ncbi.nlm.nih.gov/pubmed/26252214
http://dx.doi.org/10.1371/journal.pone.0134879

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