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Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis Mediated by YhdE Dimerization
YhdE is a Maf-like (multicopy associated filamentation) protein that primarily acts as dTTPase to hydrolyze dTTP into dTMP and two phosphate molecules in cell metabolism pathway. Two crystal structures of YhdE have been previously determined, representing the open and closed active site conformation...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529217/ https://www.ncbi.nlm.nih.gov/pubmed/26252214 http://dx.doi.org/10.1371/journal.pone.0134879 |