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Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers

BACKGROUND: Cancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle Actin (α-SMA) is a general myofibroblast marker,...

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Detalles Bibliográficos
Autores principales: Kilvaer, Thomas K., Khanehkenari, Mehrdad Rakaee, Hellevik, Turid, Al-Saad, Samer, Paulsen, Erna-Elise, Bremnes, Roy M., Busund, Lill-Tove, Donnem, Tom, Martinez, Inigo Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529239/
https://www.ncbi.nlm.nih.gov/pubmed/26252379
http://dx.doi.org/10.1371/journal.pone.0134965