The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

Internal cleavage of the cellular prion protein generates two well characterised N-terminal fragments, N1 and N2. These fragments have been shown to bind to anionic phospholipids at low pH. We sought to investigate binding with other lipid moieties and queried how such interactions could be relevant...

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Detalles Bibliográficos
Autores principales: Haigh, Cathryn L., Tumpach, Carolin, Drew, Simon C., Collins, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529310/
https://www.ncbi.nlm.nih.gov/pubmed/26252007
http://dx.doi.org/10.1371/journal.pone.0134680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529310/
https://www.ncbi.nlm.nih.gov/pubmed/26252007
http://dx.doi.org/10.1371/journal.pone.0134680

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