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MED12 exon 2 mutations in phyllodes tumors of the breast

Exon 2 of MED12, a subunit of the transcriptional mediator complex, has been frequently mutated in uterine leiomyomas and breast fibroadenomas; however, it has been rarely mutated in other tumors. Although the mutations were also found in uterine leiomyosarcomas, the frequency was significantly lowe...

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Detalles Bibliográficos
Autores principales: Nagasawa, Satoi, Maeda, Ichiro, Fukuda, Takayo, Wu, Wenwen, Hayami, Ryosuke, Kojima, Yasuyuki, Tsugawa, Ko-ichiro, Ohta, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529349/
https://www.ncbi.nlm.nih.gov/pubmed/25865354
http://dx.doi.org/10.1002/cam4.462