B7H6-specific chimeric antigen receptors lead to tumor elimination and host anti-tumor immunity

Chimeric antigen receptor (CAR) T cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B cell leukemia in clinical trials. A CAR strategy can target any tumor surface antigens as long as an antigen-binding receptor can be generated. New CARs which target sol...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Ru, Zhang, Tong, DeMars, Leslie R., Sentman, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529373/
https://www.ncbi.nlm.nih.gov/pubmed/25830550
http://dx.doi.org/10.1038/gt.2015.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529373/
https://www.ncbi.nlm.nih.gov/pubmed/25830550
http://dx.doi.org/10.1038/gt.2015.29

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