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B7H6-specific chimeric antigen receptors lead to tumor elimination and host anti-tumor immunity
Chimeric antigen receptor (CAR) T cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B cell leukemia in clinical trials. A CAR strategy can target any tumor surface antigens as long as an antigen-binding receptor can be generated. New CARs which target sol...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529373/ https://www.ncbi.nlm.nih.gov/pubmed/25830550 http://dx.doi.org/10.1038/gt.2015.29 |