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Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization

Nicotinamide N-methyltransferase (Nnmt) methylates nicotinamide, a form of vitamin B3, to produce N1-methylnicotinamide (MNAM). Nnmt is an emerging metabolic regulator in adipocytes but its role in the liver, a tissue with the strongest Nnmt expression, is not known. In spite of its overall high exp...

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Detalles Bibliográficos
Autores principales:	Hong, Shangyu, Moreno-Navarrete, Jose M, Wei, Xiaojing, Kikukawa, Yusuke, Tzameli, Iphigenia, Prasad, Deepthi, Lee, Yoonjin, Asara, John M, Fernandez-Real, Jose Manuel, Maratos-Flier, Eleftheria, Pissios, Pavlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529375/ https://www.ncbi.nlm.nih.gov/pubmed/26168293 http://dx.doi.org/10.1038/nm.3882

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