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Delivery of large molecular protein using flat and short microneedles prepared using focused ion beam (FIB) as a skin ablation tool
Many studies have been reported in the literature on the effects of various geometries and lengths of microneedles (MNs) on transdermal drug delivery using a variety of drug molecules. In particular, sharp-tipped MNs have been used to disrupt the top layer of the skin, namely, stratum corneum (SC)....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529458/ https://www.ncbi.nlm.nih.gov/pubmed/26227622 http://dx.doi.org/10.1007/s13346-015-0252-0 |