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Murine Double-Minute 2 Homolog Single Nucleotide Polymorphisms 285 and 309 in Cervical Carcinogenesis

BACKGROUND AND OBJECTIVE: In Caucasians, the MDM2 single nucleotide polymorphism (SNP) 285 G>C (rs117039649) neutralizes the effect of 309 T>G (rs2279744), which increases MDM2 expression and impairs the p53 pathway. In this study, we examined the distribution of these two SNPs in Polish women...

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Detalles Bibliográficos
Autores principales: Roszak, Andrzej, Misztal, Matthew, Sowińska, Anna, Jagodziński, Pawel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529876/
https://www.ncbi.nlm.nih.gov/pubmed/26224627
http://dx.doi.org/10.1007/s40291-015-0153-4