Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Patients

Inhalation anesthetic isoflurane inhibits hypoxia pulmonary vasoconstriction (HPV), while dexmedetomidine (Dex) could reduce the dose of isoflurane inhalation and potentiate HPV, but the mechanism is unclear. Inhibition of reactive oxygen species (ROS) production can favor HPV during one-lung ventil...

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Detalles Bibliográficos
Autores principales: Xia, Rui, Xu, Jinjin, Yin, Hong, Wu, Huozhi, Xia, Zhengyuan, Zhou, Daiwei, Xia, Zhong-yuan, Zhang, Liangqing, Li, Haobo, Xiao, Xiaoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529970/
https://www.ncbi.nlm.nih.gov/pubmed/26273134
http://dx.doi.org/10.1155/2015/238041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529970/
https://www.ncbi.nlm.nih.gov/pubmed/26273134
http://dx.doi.org/10.1155/2015/238041

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