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Endogenous Nutritive Support after Traumatic Brain Injury: Peripheral Lactate Production for Glucose Supply via Gluconeogenesis

We evaluated the hypothesis that nutritive needs of injured brains are supported by large and coordinated increases in lactate shuttling throughout the body. To that end, we used dual isotope tracer ([6,6-(2)H2]glucose, i.e., D(2)-glucose, and [3-(13)C]lactate) techniques involving central venous tr...

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Detalles Bibliográficos
Autores principales: Glenn, Thomas C., Martin, Neil A., McArthur, David L., Hovda, David A., Vespa, Paul, Johnson, Matthew L., Horning, Michael A., Brooks, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530391/
https://www.ncbi.nlm.nih.gov/pubmed/25279664
http://dx.doi.org/10.1089/neu.2014.3482