STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer

The importance of store-operated Ca(2+) entry (SOCE) and the role of its key molecular regulators, STIM1 and ORAI1, in the development of cancer are emerging. Here, we report an unexpected dual function of SOCE in prostate cancer progression by revealing a decrease in the expression of STIM1 in huma...

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Detalles Bibliográficos
Autores principales: Xu, Yingxi, Zhang, Shu, Niu, Haiying, Ye, Yujie, Hu, Fen, Chen, Si, Li, Xuefei, Luo, Xiaohe, Jiang, Shan, Liu, Yanhua, Chen, Yanan, Li, Junying, Xiang, Rong, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530453/
https://www.ncbi.nlm.nih.gov/pubmed/26257076
http://dx.doi.org/10.1038/srep11754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530453/
https://www.ncbi.nlm.nih.gov/pubmed/26257076
http://dx.doi.org/10.1038/srep11754

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