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The human urothelial tight junction: claudin 3 and the ZO-1α(+) switch

OBJECTIVE: Tight junctions are multicomponent structures, with claudin proteins defining paracellular permeability. Claudin 3 is a candidate for the exceptional “tightness” of human urothelium, being localised to the terminal tight junction (TJ) of superficial cells. Our aim was to determine whether...

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Detalles Bibliográficos
Autores principales: Smith, Nicholas J, Hinley, Jennifer, Varley, Claire L, Eardley, Ian, Trejdosiewicz, Ludwik K, Southgate, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530542/
https://www.ncbi.nlm.nih.gov/pubmed/26269793
http://dx.doi.org/10.14440/bladder.2015.33