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Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells

CGG repeat expansions in the Fragile X mental retardation 1 (FMR1) gene are responsible for a family of associated disorders characterized by either intellectual disability and autism Fragile X Syndrome (FXS), or adult-onset neurodegeneration Fragile X-associated Tremor/Ataxia Syndrome. However, the...

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Detalles Bibliográficos
Autores principales: Peschansky, Veronica J., Pastori, Chiara, Zeier, Zane, Motti, Dario, Wentzel, Katya, Velmeshev, Dmitry, Magistri, Marco, Bixby, John L., Lemmon, Vance P., Silva, José P., Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530595/
https://www.ncbi.nlm.nih.gov/pubmed/26322075
http://dx.doi.org/10.3389/fgene.2015.00263