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Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation

The tumour suppressor Merlin, encoded by the gene NF2, is frequently mutated in the autosomal dominant disorder neurofibromatosis type II, characterised primarily by the development of schwannoma and other glial cell tumours. However, NF2 is expressed in virtually all analysed human and rodent organ...

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Detalles Bibliográficos
Autores principales: Zoch, Ansgar, Mayerl, Steffen, Schulz, Alexander, Greither, Thomas, Frappart, Lucien, Rübsam, Juliane, Heuer, Heike, Giovannini, Marco, Morrison, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530865/
https://www.ncbi.nlm.nih.gov/pubmed/26258444
http://dx.doi.org/10.1371/journal.pone.0129151