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Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation
The tumour suppressor Merlin, encoded by the gene NF2, is frequently mutated in the autosomal dominant disorder neurofibromatosis type II, characterised primarily by the development of schwannoma and other glial cell tumours. However, NF2 is expressed in virtually all analysed human and rodent organ...
Autores principales: | Zoch, Ansgar, Mayerl, Steffen, Schulz, Alexander, Greither, Thomas, Frappart, Lucien, Rübsam, Juliane, Heuer, Heike, Giovannini, Marco, Morrison, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530865/ https://www.ncbi.nlm.nih.gov/pubmed/26258444 http://dx.doi.org/10.1371/journal.pone.0129151 |
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