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Artificial Loading of ASC Specks with Cytosolic Antigens

Inflammasome complexes form upon interaction of Nod Like Receptor (NLR) proteins with pathogen associated molecular patterns (PAPMS) inside the cytosol. Stimulation of a subset of inflammasome receptors including NLRP3, NLRC4 and AIM2 triggers formation of the micrometer-sized spherical supramolecul...

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Detalles Bibliográficos
Autores principales: Sahillioğlu, Ali Can, Özören, Nesrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530869/
https://www.ncbi.nlm.nih.gov/pubmed/26258904
http://dx.doi.org/10.1371/journal.pone.0134912