Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia

Diamond Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome with clinical features of red cell aplasia and variable developmental abnormalities. Most affected patients have heterozygous loss of function mutations in ribosomal protein genes but the pathogenic mechanism is still unknown...

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Detalles Bibliográficos
Autores principales: Ge, Jingping, Apicella, Marisa, Mills, Jason A., Garçon, Loïc, French, Deborah L., Weiss, Mitchell J., Bessler, Monica, Mason, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530889/
https://www.ncbi.nlm.nih.gov/pubmed/26258650
http://dx.doi.org/10.1371/journal.pone.0134878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530889/
https://www.ncbi.nlm.nih.gov/pubmed/26258650
http://dx.doi.org/10.1371/journal.pone.0134878

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