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Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells

Microenvironment plays an important role in epithelial-mesenchymal transition (EMT) and stemness of cells in hepatocellular carcinoma (HCC). Epithelial cell adhesion molecule (EpCAM) is known as a tumor stemness marker of HCC. To investigate the relationship between microenvi-ronment and stemness, w...

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Detalles Bibliográficos
Autores principales: NAGAHARA, TERUYA, SHIRAHA, HIDENORI, SAWAHARA, HIROAKI, UCHIDA, DAISUKE, TAKEUCHI, YASUTO, IWAMURO, MASAYA, KATAOKA, JUNRO, HORIGUCHI, SHIGERU, KUWAKI, TAKESHI, ONISHI, HIDEKI, NAKAMURA, SHINICHIRO, TAKAKI, AKINOBU, NOUSO, KAZUHIRO, YAMAMOTO, KAZUHIDE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530901/
https://www.ncbi.nlm.nih.gov/pubmed/26165819
http://dx.doi.org/10.3892/or.2015.4126