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Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells

An epidemiological study showed that green tea consumption is associated with a reduced risk of hematopoietic malignancy. The major green tea polyphenol epigallocatechin-3-O-gallate (EGCG) is reported to have anticancer effects. Chronic myeloid leukemia (CML) is a major hematopoietic malignancy char...

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Detalles Bibliográficos
Autores principales: HUANG, YUHUI, KUMAZOE, MOTOFUMI, BAE, JAEHOON, YAMADA, SHUHEI, TAKAI, MIKA, HIDAKA, SHIORI, YAMASHITA, SHUYA, KIM, YOONHEE, WON, YEONGSEON, MURATA, MOTOKI, TSUKAMOTO, SHUNTARO, TACHIBANA, HIROFUMI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530928/
https://www.ncbi.nlm.nih.gov/pubmed/26135316
http://dx.doi.org/10.3892/or.2015.4086