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ATP Binding Cassette Transporter Mediates Both Heme and Pesticide Detoxification in Tick Midgut Cells

In ticks, the digestion of blood occurs intracellularly and proteolytic digestion of hemoglobin takes place in a dedicated type of lysosome, the digest vesicle, followed by transfer of the heme moiety of hemoglobin to a specialized organelle that accumulates large heme aggregates, called hemosomes....

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Detalles Bibliográficos
Autores principales: Lara, Flavio Alves, Pohl, Paula C., Gandara, Ana Caroline, Ferreira, Jessica da Silva, Nascimento-Silva, Maria Clara, Bechara, Gervásio Henrique, Sorgine, Marcos H. F., Almeida, Igor C., Vaz, Itabajara da Silva, Oliveira, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530934/
https://www.ncbi.nlm.nih.gov/pubmed/26258982
http://dx.doi.org/10.1371/journal.pone.0134779