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Targeted Intracellular Delivery of Resveratrol to Glioblastoma Cells Using Apolipoprotein E-Containing Reconstituted HDL as a Nanovehicle

The objective of this study is to transport and deliver resveratrol to intracellular sites using apolipoprotein E3 (apoE3). Reconstituted high-density lipoprotein (rHDL) bearing resveratrol (rHDL/res) was prepared using phospholipids and the low-density lipoprotein receptor (LDLr)-binding domain of...

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Detalles Bibliográficos
Autores principales: Kim, Sea H., Adhikari, Birendra Babu, Cruz, Siobanth, Schramm, Michael P., Vinson, Joe A., Narayanaswami, Vasanthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530947/
https://www.ncbi.nlm.nih.gov/pubmed/26258481
http://dx.doi.org/10.1371/journal.pone.0135130