Joint MiRNA/mRNA Expression Profiling Reveals Changes Consistent with Development of Dysfunctional Corpus Luteum after Weight Gain

Obese women exhibit decreased fertility, high miscarriage rates and dysfunctional corpus luteum (CL), but molecular mechanisms are poorly defined. We hypothesized that weight gain induces alterations in CL gene expression. RNA sequencing was used to identify changes in the CL transcriptome in the ve...

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Detalles Bibliográficos
Autores principales: Bradford, Andrew P., Jones, Kenneth, Kechris, Katerina, Chosich, Justin, Montague, Michael, Warren, Wesley C., May, Margaret C., Al-Safi, Zain, Kuokkanen, Satu, Appt, Susan E., Polotsky, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530955/
https://www.ncbi.nlm.nih.gov/pubmed/26258540
http://dx.doi.org/10.1371/journal.pone.0135163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530955/
https://www.ncbi.nlm.nih.gov/pubmed/26258540
http://dx.doi.org/10.1371/journal.pone.0135163

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