Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

In the present study, solid dispersion nanoparticles with a hydrophilic polymer and surfactant were developed using the supercritical antisolvent (SAS) process to improve the dissolution and oral absorption of megestrol acetate. The physicochemical properties of the megestrol acetate solid dispersio...

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Detalles Bibliográficos
Autores principales: Ha, Eun-Sol, Kim, Jeong-Soo, Baek, In-hwan, Yoo, Jin-Wook, Jung, Yunjin, Moon, Hyung Ryong, Kim, Min-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531043/
https://www.ncbi.nlm.nih.gov/pubmed/26345723
http://dx.doi.org/10.2147/DDDT.S90706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531043/
https://www.ncbi.nlm.nih.gov/pubmed/26345723
http://dx.doi.org/10.2147/DDDT.S90706

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