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Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability

It is now thought that atherosclerosis, although due to increased plasma lipids, is mainly the consequence of a complicated inflammatory process, with immune responses at the different stages of plaque development. Increasing evidence points to a significant role of Toll-like receptor 4 (TLR4), a ke...

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Detalles Bibliográficos
Autores principales: Gargiulo, Simona, Gamba, Paola, Testa, Gabriella, Rossin, Daniela, Biasi, Fiorella, Poli, Giuseppe, Leonarduzzi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531071/
https://www.ncbi.nlm.nih.gov/pubmed/25757594
http://dx.doi.org/10.1111/acel.12322