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Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance

The role of lymphatic vessels is to transport fluid, soluble molecules, and immune cells to the draining lymph nodes. Here, we analyze how the aging process affects the functionality of the lymphatic collectors and the dynamics of lymph flow. Ultrastructural, biochemical, and proteomic analysis indi...

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Detalles Bibliográficos
Autores principales: Zolla, Valerio, Nizamutdinova, Irina Tsoy, Scharf, Brian, Clement, Cristina C, Maejima, Daisuke, Akl, Tony, Nagai, Takashi, Luciani, Paola, Leroux, Jean-Christophe, Halin, Cornelia, Stukes, Sabriya, Tiwari, Sangeeta, Casadevall, Arturo, Jacobs, William R, Entenberg, David, Zawieja, David C, Condeelis, John, Fooksman, David R, Gashev, Anatoliy A, Santambrogio, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531072/
https://www.ncbi.nlm.nih.gov/pubmed/25982749
http://dx.doi.org/10.1111/acel.12330