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Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide

Muscle aging is associated with changes in myeloid cell phenotype that may influence age-related changes in muscle structure. We tested whether preventing age-related reductions in muscle neuronal nitric oxide synthase (nNOS) would obviate age-related changes in myeloid cells in muscle. Our findings...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wehling-Henricks, Michelle, Samengo, Giuseppina, Tidball, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531081/
https://www.ncbi.nlm.nih.gov/pubmed/26009878
http://dx.doi.org/10.1111/acel.12350