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Paternal age and telomere length in twins: the germ stem cell selection paradigm

Telomere length, a highly heritable trait, is longer in offspring of older fathers. This perplexing feature has been attributed to the longer telomeres in sperm of older men and it might be an ‘epigenetic’ mechanism through which paternal age plays a role in telomere length regulation in humans. Bas...

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Detalles Bibliográficos
Autores principales: Hjelmborg, Jacob B, Dalgård, Christine, Mangino, Massimo, Spector, Tim D, Halekoh, Ulrich, Möller, Sören, Kimura, Masayuki, Horvath, Kent, Kark, Jeremy D, Christensen, Kaare, Kyvik, Kirsten O, Aviv, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531084/
https://www.ncbi.nlm.nih.gov/pubmed/25865872
http://dx.doi.org/10.1111/acel.12334